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GLP-1 is an incretin hormone that enhances insulin secretion, suppresses glucagon, slows gastric emptying, and acts on the hypothalamus to promote satiety ( Since 2020, multiple randomized trials have confirmed the significant benefits of GLP-1 RAs in adolescents, which can induce substantial, clinically meaningful weight loss and metabolic benefits in adolescents with obesity

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In vitro and in vivo toxicity evaluation of cationic PDMAEMA-PCL-PDMAEMA micelles as a carrier of curcumin