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Semaglutide: A Comprehensive Overview Semaglutide, a medication that has garnered significant attention in the medical community, represents a novel approach in the treatment of not just type 2 diabetes but also obesity, and potentially, as recent discussions suggest, Irritable Bowel Syndrome (IBS)
Liraglutide Liraglutide is a long-acting GLP-1R agonist that is administered subcutaneously, as a treatment of type 2 diabetes
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Nrf2-ARE pathway regulates induction of Sestrin-2 expression
Primary mouse peritoneal macrophages, mouse macrophage-like RAW 264.7 cells, and human monocytic THP-1 cells were transfected with GSTP encoding expression vector (pcDNA3.1-Flag-GSTP) or empty vector (pcDNA3.1), followed by stimulation of LPS (500 ng/ml) for 18 h, and the levels of HMGB1 in the culture medium were determined by ELISA