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In summary, we identified ER stress as the main adaptive stress response caused by AQ-QI and DEAQ-QI and evaluated the protective role of GSTP1 using a transfected HepG2 cell model
All other chemicals were purchased from Sigma-Aldrich (St
This is a gap in the current evidence base
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Use a dosage of 1 mcg/kg to 10 mcg/kg body weight for subcutaneous or intramuscular injection
Research protocols typically dose MOTS-c at 515 mg/kg subcutaneously and 5-Amino-1MQ at 2550 mg/kg orally, with staggered introduction recommended to isolate each compound's contribution before full stacking
