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For constipation management, increasing dietary fiber gradually (not suddenly, which can worsen symptoms), drinking at least 60 to 80 ounces of water daily, and incorporating light movement like walking can provide relief without medication

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Splitting, chewing, or crushing the tablet also breaks down this barrier, making the drug less effective

Working with physicians to document obesity-related comorbidities can sometimes facilitate coverage approval

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If successful, these advances could lower entry barriers and reduce some of the challenges associated with long term use