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The brain contains the body's second-highest concentration of copper after the liver, where this essential metal serves critical roles in neurotransmitter synthesis, mitochondrial function, and antioxidant defense systems

10.1016/j.cmet.2022.02.009Epub 2022 Mar 10

In brief, the mice were administered a daily topical application of 62.5 mg of 5% imiquimod cream (Mingxinlidi, Sichuan, China) on their shaved backs for seven consecutive days

This peptide promotes cell migration and differentiation, complements angiogenesis, and supports tissue remodeling

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Zn is an essential micronutrient for plants and humans 31