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For instance, it is unlikely that we can detect oxidative modifications of certain enzymes or transcription factors that are expressed in very low quantities, although these proteins may contain Cys residues that can be oxidatively-modified following MDMA exposure

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You can read the abstract of this article at Tesofensine, a monoamine reuptake inhibitor for the treatment of obesity Tesofensine is a drug being developed by NeuroSearch A/S to potentially treat obesity