Hydroxyl radical formation resulting from the interaction of nickel complexes of L-histidine, glutathione or L-cysteine and hydrogen peroxide
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Current therapeutic strategies of OA are largely concentrated in symptomatic management, such as oral non-steroidal anti-inflammatory drugs (NSAIDs) and intra-articular steroid injections, which only provide temporary relief 3,4
The dose-dependent activation of the FAK-paxillin pathway was confirmed as a key mechanism
Although paclitaxel is known to induce apoptosis, recent research has highlighted the role of necroptosis, a form of programmed necrotic cell death, in chemobrain (Zhou et al., 2024)
Dysfunctional Nrf2-Keap1 Redox Signaling in Skeletal Muscle of the Sedentary Old