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During Phase I many free radicals are generated making antioxidants a critical component to a well-rounded program

In a substudy of 178 patients from the SUSTAIN 8 trial on semaglutide as a diabetes treatment, the average proportion of lean mass loss was nearly identical at 40%, despite lower doses and less total weight loss than in the STEP 1 trial

Among the potential therapeutic approaches, interventions targeting endothelial dysfunction (such as RAAS modulators, and flavonoids) and persistent inflammation (e.g., antioxidants, vitamin C, vitamin D, and AMPK activators like metformin) appear particularly promising

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Brock et al

Thyroidectomy: Thyroidectomy refers to the removal of the thyroid gland