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Synonyms Peptilift Leucine Enkephalin Leu-Enkephalin References A leu-enkephalin depresses transmission from muscle and skin non-nociceptors to first-order feline spinal neurones Author(s): Jankowska E, Schomburg ED DOI: 10.1111/j.1469-7793.1998.513bk.x Biomimetic endorphin for wrinkle lifting in a daily cosmetic remedy Author(s): Ritamaria Di Lorenzo, Antonietta Bernardi, Federica Forgione, Antonia Sacchi, Sonia Laneri In vitro skin penetration and degradation of peptides and their analysis using a kinetic model Author(s): Ogiso T, Iwaki M, Tanino T, Yono A, Ito A Leucine-enkephalin promotes wound repair through the regulation of hemidesmosome dynamics and matrix metalloprotease Author(s): Yang DJ, Lee KS, Ko CM, Moh SH, Song J, Hur LC, Cheon YW, Yang SH, Choi YH, Kim KW DOI: 10.1016/j.peptides.2015.12.010 Regulated proenkephalin expression in human skin and cultured skin cells Author(s): Slominski AT, Zmijewski MA, Zbytek B, Brozyna AA, Granese J, Pisarchik A, Szczesniewski A, Tobin DJ Localization of enkephalin immunoreactivity in diverse tissues and cells of the developing and adult rat Author(s): Zagon IS, Rhodes RE, McLaughlin PJ

This population-specific safety evidence is more relevant for clinical application than data from exclusively healthy volunteers would be

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Phase II study of ganitumab, a fully human anti-type-1 insulin-like growth factor receptor antibody, in patients with metastatic Ewing family tumors or desmoplastic small round cell tumors

Based upon the questionnaires, there was a significant improvement in the treatment group in behavior upon awakening, energy, daytime productivity, grouchiness, mood, and mental alertness compared with placebo

At least, not in a healthy way