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The jieduan-niwan (Jdnw) formula ameliorates hepatocyte apoptosis: A study of the inhibition of E2f1-mediated apoptosis signaling pathways in acute-on-chronic liver failure (Aclf) using rats

In clinical trials, people taking this drug saw significant weight loss

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In contrast, there was no evidence of carcinogenic activity in male rats that received up to 0.7 times or mice at up to 1.2-1.4 times the MHDD, based on a body surface area comparison

These examples show how dosage and frequency change based on goals

Clark DW, Palle K (2016) Aldehyde dehydrogenases in cancer stem cells: potential as therapeutic targets