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doi: 10.1016/j.tice.2025.102998, 83
These mediators promote extracellular matrix remodeling, vascular activation, and further immune recruitment, creating a self-sustaining inflammatory niche that facilitates OA progression (Wang B
The evidence supports the opposite: when governance is weak, the same vulnerabilities appear everywhere because the underlying drivershuman incentives, operational pressure, inadequate segregation of duties, and insufficient QU oversightare universal
For example, use GHK-Cu in one routine and retinoids or acids in another
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