Diarrhea: Diarrhea is another common gastrointestinal side effect of GLP-1 medications, characterized by loose or watery stools
Participants in clinical trials are closely observed for potential adverse reactions, including gastrointestinal symptoms, changes in laboratory values, or unexpected systemic effects
Target dose: 10 to 15 grams daily, increased gradually over 2 to 3 weeks
Glycemic efficacy varies across the GLP-1 class
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Liraglutide, a GLP-1 Receptor Agonist, Inhibits Vascular Smooth Muscle Cell Proliferation by Enhancing AMP-Activated Protein Kinase and Cell Cycle Regulation, and Delays Atherosclerosis in ApoE Deficient Mice