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In Phase 2, the 12 mg group lost an average of 24.2% body weight over 48 weeks
Research shows semaglutide significantly reduces waist circumference and waist-to-height ratio, indicating meaningful abdominal fat loss
As an obesity medicine physician scientist who regularly cares for patients with complex inflammatory conditions, this study reinforces what many of us have suspected clinicallythat the benefits of GLP-1 receptor agonists extend well beyond blood sugar control and weight loss and may fundamentally alter the disease trajectory for some of our highest-risk patients. Although this study cannot prove a causal link between GLP-1 medication and the effects seen on the patients taking them, it opens the door to future combinations of treatments for autoimmune disease with GLP-1 drugs
While the scale might show a pound or two in the first week, clinically significant weight loss, defined as 5% or more of starting body weight, typically requires four to twelve weeks depending on the medication and dose
Tirzepatide labels note that delayed gastric emptying during initiation and dose escalation can affect absorption of oral contraceptives, so reproductive planning should be discussed with your clinician
Our treatments are clinically overseen by Dr
