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As PTDM and chronic kidney disease are prevalent comorbidities in liver transplant patients, and with the increasing trend of obesity, it is crucial to further investigate and understand the potential benefits and challenges of utilizing GLP-1 RAs and SGLT-2 inhibitors in this population

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The FDA requires a CVOT for all antidiabetic agents per its 2008 guidance, and a GLP-1-class CVOT is standard for obesity agents following SELECT (semaglutide 2.4 mg, N=17,604) which showed a 20% reduction in MACE [11]

Let-7 suppresses B cell activation through restricting the availability of necessary nutrients

Skip grapefruit entirely if you take statins, certain blood pressure medications, or immunosuppressants

Mucormycosis is particularly seen in individuals with advanced diabetes