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Employer-sponsored plans have been expanding coverage approximately 45% of large employers now include at least one GLP-1 on their formulary for obesity treatment, up from about 25% in 2023

Diarrhea or constipation Digestive changes occur as semaglutide slows gastric emptying

This hypothesis was also validated in a lipopolysaccharide (LPS)-induced systemic inflammation rat model (28)

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Effectiveness and Side Effects: Semaglutide appears to result in greater weight loss compared to liraglutide, but it is also associated with more frequent side effects

Oral formulations of GLP-1 agonists exist but show reduced efficacy compared to injectable versions