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Unlike orthosteric agonists, 52 did not cause receptor desensitization even with repeated dosing, and is currently being evaluated in clinical trials for its efficacy and safety in mild to moderate AD patients

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Also, some of the other indications, like kidney disease and cardiovascular disease, show benefits irrespective of weight loss and glucose lowering, and should be continued if you have those conditions for their benefit

take 1 capsule 15 minutes before a meal (may take up to 2/day)

Originating in the subarachnoid space, CSF traverses periarterial spaces, mixes with interstitial fluid in the brain parenchyma, and ultimately exits via perivenous spaces [199]