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Methods Ethics statement Data analysis utilizing the TriNetX platform received approval from the Institutional Review Board of Chi-Mei Hospital (No: 11202-002), as well as approval from the institutional review boards of all participating hospitals

These receptors are crucial for controlling blood sugar and hunger

It does not engage the GIP receptor (Tirzepatide's second target) or the Glucagon receptor (Retatrutide's third target)

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Promising candidates such as N-acetylcysteine, glutathione precursors, coenzyme Q10, vitamin E, and polyphenols have been found to be potentially effective against oxidative damage and enhancing behavioral outcomes

Repeat the rinsing with PBS three times and then add 300 L of FITC-phalloidin (Solarbio, Beijing, China) solution, incubate for 30 min in the dark, then wash three times with PBS, Add DAPI (4,6-diamidino-2-phenylindole) staining solution (Solarbio, Beijing, China) for 10 min and seal with glycerol