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While A42 likely plays a major role during early stages of the disease, it has been proposed that Tau pathology plays a prominent role in the symptomatic (late) stages of AD as a key driver of the neurodegeneration (Hyman, 2011

The injection sites for the medication patients should inject in the fatty areas of the upper legs, arms, or stomach, and avoid veins or muscles

Moreover, the gut microbiota affects behavior, regulates neurotransmitter production in the gut and brain, and plays a role in brain development and myelination patterns (Bolyen et al., 2019

The colon is more responsive to oxidative damage because of the relatively short amount of antioxidants accessible in the mucosa

However, as this analysis was conducted post hoc, the findings should be interpreted with caution and considered hypothesis-generating rather than evidence of superiority between agents

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