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PMID 31712552

The absence of tissue growth effects also means AOD-9604 avoids many common side effects of growth hormone therapy including joint pain and swelling from connective tissue proliferation, carpal tunnel syndrome from tissue expansion, edema and fluid retention from protein synthesis and sodium retention, and concerns about growth-promoting effects in individuals with tumor history

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NAD + promotes glycolysis by facilitating the enzymatic reactions catalyzed by GAPDH and lactate dehydrogenase (LDH), which use NAD + as a coenzyme

Clinical application recommendations of mucoactive/antioxidant medicines Expectorant/antioxidant medicine recommendation from COPD guidelines GOLD 2013 63 indicated for expectorant/antioxidant medicine use for treatment of hypersecretion in COPD airway, as may induce recurrent infection and airway obstruction