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Although L-cysteine is a minor scavenger of oxidative stress, its most important role is reviving glutathione, one of the most powerful antioxidants in the body

However, the prospective Shanghai Osteoarthritis Cohort study showed that GLP-1RA users with KOA and diabetes exhibited a greater reduction in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total and pain score and a lower occurrence of knee surgery compared to controls

Gressmann et al

It is recommended to take Glutathione injections 1-3 times per week for about 8-12 weeks

For example, a study discovered that obese people who took oral glutathione had significant increases in insulin sensitivity without changing their oxidative stress

2004 [cited 2020 Dec 23];39(1)