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2019 [Available from: Accessed: 13 April 2023]

Note that metformin alone rarely causes hypoglycaemia, but the risk may be higher with sulphonylureas or insulin Medicines metabolised by CYP3A4 or CYP2D6 enzymes : Berberine may inhibit these enzymes, potentially affecting blood levels of many medicines P-glycoprotein substrates : Berberine may affect transport of certain medicines, including some immunosuppressants and cardiac drugs Berberine products should be avoided during pregnancy and breastfeeding due to insufficient safety data

If tanning is the goal, use MT-2 during TRT off-periods or explore lower-risk alternatives

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Published on January 1st, 2026