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Liver disease is a significant contributor to illness and death globally

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It is likely that variations in experimental methods, biological systems, as well as the distinct metabolic characteristics of cells contributed to the variability in reported results 18,23

The albumin quotient (Q alb ), a key marker of BBB permeability, has been found to be elevated in several studies involving individuals with preclinical AD, mild cognitive impairment (MCI), and established AD itself (Halliday et al

When combined, patients may experience: Markedly reduced food intake, potentially leading to inadequate nutrition Difficulty consuming sufficient calories to maintain healthy body function Increased risk of nutrient deficiencies if dietary intake becomes severely restricted Challenges in maintaining adequate hydration Cardiovascular considerations also warrant attention

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