A recent study with platinum resistant HGSC ovarian cancer cell lines OVCAR4 and OVCAR5 shows that it is possible to decrease the uptake of cholesterol through SR-B1 with treating the cells with synthetic SR-B1-targeting, HDL-mimicking nanoparticles, and that it leads to decreased cancer cell viability [117]
(PubMed) Cardoso BR, Braat S, Graham RM
Moreover, the result also infers that extracts of P
In line with histological observations, EtOH feeding caused a 50% increase in total hepatic TG content in WT mice, but had no effect on the hepatic TG content in KO mice (Table 1)
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