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Conscious of the importance of all the above, we argue for the need of and inquisitive mechanistic and clinically applied research to inform stakeholders about the potential benefits and harms of GLP-1RAs

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Interestingly, according to the weight loss and increased IGF-2 levels, patients treated with liraglutide showed changes in adipose tissue distribution with reduction of the visceral adipose tissue, which expresses IGF-2, IGF-2 receptors and IR