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Not only do you need less of the active ingredient to achieve better results, but the steady absorption over time will increase the benefits between applications

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Wang L, Wang X, Zhu XM, Liu YQ, Du WJ, Ji J, He X, Zhang CF, Li F, Guo CR, Wang CZ, Yuan CS (2017) Gastroprotective effect of alkaloids from cortex phellodendri on gastric ulcers in rats through neurohumoral regulation