glp 1 six in one directions Designing GLP-1 delivery: structural perspectives and formulation approaches for optimized therapy Here's How To Properly Inject

Lancet 368 , 16961705 (2006)

Native GLP-1 is degraded within 23 min in the circulation

The following are used to make these patches: Note: The actual GLP-1 agonist drug patches containing semaglutide are still under trial are known to reduce appetite, manage cravings and hunger, and give a feeling of fullness 4

Hypoglycaemia: As noted above, the risk with incretin monotherapy is generally low in healthy individuals but is heightened by concurrent use of insulin or sulphonylureas, extreme caloric restriction, or prolonged strenuous exercise

And individual experiences like this are really encouraging

Vagal mediation of GLP-1s effects on food intake and glycemia