Obesity is a known risk factor for breast cancer, and weight loss may lower the risk of developing the disease
In experimental models, body weight gains have been observed, possibly connected to both food intake regulation and hormonal influences independent of growth hormone
Additionally, other issues, like liver disease, might become aggravated by fluctuating thyroid hormone levels, even when the liver cells are capable of handling their own levels of oxidative stress
While questions about long-term safety remain, the potential to improve patient outcomes by focusing on composition, not just weight, is worth watching as the full trial data emerges
Like other GLP-1 drugs , Zepbound can also lead to other GI side effects such as: Nausea Diarrhea Vomiting Constipation Gas Acid reflux Fortunately, Zepbound stomach pain and other GI side effects are often mild to moderate and tend to improve as the body gets used to slower digestion over the first several weeks
(Note: I was asked by the journals editor-in-chief* to write an editorial that accompanies the remarkable new research paper