Kidney/liver: No routine dose adjustment is typically required, but monitor closelysevere GI effects can cause dehydration and worsen kidney function
Thirdly, and perhaps most notably for weight management, GLP-1 slows gastric emptyingmeaning food stays in the stomach longer, promoting feelings of fullness (though this effect may worsen symptoms in people with gastroparesis)
Liraglutide 3.0 mg and intensive behavioral therapy (IBT) for obesity in primary care: the SCALE IBT randomized controlled trial
This study has several limitations
Because GLP-1 drugs affect the brain's reward pathways, they may shift how you feel emotionally, including your interest in activities you once enjoyed
At ACR Convergence 2025, researchers from Toronto and NYU reported that PsA patients starting GLP-1 receptor agonists had significant improvements in joint counts, CRP, pain scores, and DAPSA disease activity scores within one year of treatment. Whats interesting is that you dont seem to need a large dose to see these benefits