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The product is prepared under regulatory oversight (state pharmacy boards inspect compounding pharmacies), but the documentation standard is not as uniform as FDA-registered manufacturing

At the same time, researchers emphasize that more data is needed, particularly regarding longer-term exposure throughout pregnancy and rare outcomes

They have significant anxiety around the weight gain that they're experiencing. The Infant Risk Center at Texas Tech University, which provides guidance on medication safety while breastfeeding, also reports overwhelming interest from lactating women in taking semaglutide to control weight

Kim YJ, Kim EH, Hahm KB

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Its molecular target is nicotinamide N-methyltransferase (NNMT), a cytosolic S-adenosyl-L-methionine-dependent methyltransferase that converts nicotinamide to 1-methylnicotinamide, consuming SAM and releasing S-adenosylhomocysteine