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The biological mechanism linking folate and B 12 during pregnancy with offspring neurodevelopment is likely to be via the roles of these vitamins in OCM and the generation of SAM, which in turn is essential in donating methyl groups in numerous transmethylation reactions including the synthesis of neurotransmitters and DNA methylation (Reference Bailey, Stover and McNulty5,Reference Allen, Miller and De Groot7)

Similarly, an increase in ROS level due to function failure of a mitochondrial situated ATP-dependent protease FtSH4 contributes to leaf senescence by regulating the signalling and accumulation of WRKY-reliant salicylic acid (SA) [65]

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Aqueous humor proteomic alterations associated with visual field index parameters in glaucoma patients: a pilot study

Three studies, including 2 cohort studies and 1 case-control study, have pointed out the direct correlation between GD and increased risk or severities of depression