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Malabsorption from coeliac disease, Crohns, gastric surgery or long-term metformin and proton-pump inhibitors accounts for much of the rest

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At the same time, the available publications mainly concern preclinical models and metabolic studies on the analogue of the AOD9604 , therefore interpretation of the results should take into account the experimental nature of this molecule and the fact that the scope of modern, high-quality clinical data is limited