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CDK11 p58 or CDK11 p58 -cyclin L2 (1319)-SAP30BP was prepared in ITC buffer to a final composition of 37 M protein, 200 mM KCl, 2 mM MgCl 2 , 20 mM HEPES-KOH pH 7.9, 1 mM TCEP, 2.5% (v/v) glycerol, 2% (v/v) DMSO

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Ethics statement The animal study was approved by Expert committee for ensuring the welfare of experimental animals of the Masaryk University

For compounded versions, the dosage calculator helps determine exact volumes based on concentration and target dose

This helps ward off megaloblastic anemia caused by B12 deficiency

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