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Retatrutide, with triple-target effects (it works at the two receptors mentioned above and the glucagon receptor), caused people to lose about a quarter of their body weight after a year in a Phase II study (Jastreboff AM et al, N Engl J Med 2023;389(6):514526), although a follow-up study found the weight loss more in line with tirzepatide

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An in-depth understanding of the causal relationships between various metabolites and epilepsy and an exploration of related mechanisms may provide new targets for epilepsy screening and prevention

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Improved Blood Sugar Control: Beneficial for weight management and overall health, particularly for those with type 2 diabetes

Claims with weak, preliminary, preclinical, or unsupported evidence are identified as such rather than presented as established medical benefit