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For those who qualify, prescription GLP-1 medications, combined with lifestyle support, offer the most proven approach for achieving significant and sustainable weight loss
The sample of symptomatic cases was small because a number of patients were lost during the follow-up period, and the evaluation, based only on plain radiograph, may have been inaccurate
Key highlights Tirzepatide is a once-weekly injectable medication that acts as a dual agonist of GLP-1 & GIP receptors, while orforglipron is a daily oral GLP-1 receptor agonist
Weight regain after a period of weight loss is really common, no matter what approach you take, says Sam West, lead author of the study and a research scientist at the University of Oxford, who specializes in integrated metabolism