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Inflammatory cytokines IL-1 and IL-18 present in the ovarian tissue and FF in PCOS patients alter the follicular microenvironment by binding to receptors like IL-1R and TLR4 on the GCs, activating NF-B, which subsequently translocates into the nucleus (50)

Magnes Res 2023;36(2):31-39

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Myo-inositol supplementation reduces the amount of gonadotropins and length of ovarian stimulation in women undergoing ivf: A systematic review and meta-analysis of randomized controlled trials

This blocks the degradation process and restores iron export (Huang et al., 2022)