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Polyphenols Polyphenols are secondary metabolites of plants with antidiabetic effects, whose benefits are related to the stimulation of insulin and GLP-1 secretion, as well as increasing GLP-1 half-life by inhibiting DPP-4 activity [187]

doi:10.5664/jcsm.7102 Lin CH, Lurie RC, Lyons OD

supplements GLP-1 medications like semaglutide ( Ozempic and Wegovy) and tirzepatide ( Zepbound and Mounjaro) are FDA-approved prescription drugs specifically designed to manage type 2 diabetes and/or aid in weight loss

Still other peptides not on the list were flagged for potential concerns

Beyond these metabolic changes, cardiac fibroblasts in the HFpEF plus semaglutide condition display broad changes in ECM, ECM modifying enzymes, and ECM regulators