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However, within this context, a systematic review and a meta-analysis have reported that exclusively breastfed infants wake more frequently at night [68, 69], while there is no difference in night or 24-hour sleep duration compared to formula-fed infants [68]

Other investigational compounds like acamprosate, neramexane, and AM-101 have also shown promise in clinical trials, though none are yet approved, highlighting the ongoing research need (Che et al., 2025)

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On your first visit, your board-certified orthodontist will perform a complimentary exam of your smile, talk about your goals and needs, then give you honest, no-pressure guidance on the best path forward