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Impairments range from subtle effects that can only be detected with special tests at levels between 0.001-0.029%, to problems with concentration, reflexes, motor control, and more, including a serious possibility of death at 0.50% or more.

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Congestive heart failure (CHF)

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Physiol Rev 63(4):14201480

barbarum berries for 90 days significantly increased macular pigment optical density (MPOD) in healthy middle-aged adults