glp-1 long term weight loss Those discontinuing medications rapidly regained What are GLP-1s? | Mendinground

The early phase begins within minutes of eating, when nutrients in the upper gastrointestinal tract trigger neural and hormonal signals that stimulate L-cells even before food reaches the distal intestine

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This does not mean weight regain is inevitable or total, but it does reflect an important biological reality: GLP-1 medications work in part by suppressing appetite and slowing gastric emptying, and when the medication stops, those effects stop too

Discontinuations of one or two years without resuming GLP-1 use resulted in a 14% or 22% increased risk of cardiovascular events, respectively, compared to staying on the drugs

By connecting the gut and brain, it helps control appetite, blood sugar, and overall health

Especially at the start of GLP-1 therapy as your body is adjusting to the medication