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In the third screening step, mutant SpyCatchers that showed strong inhibition when modified with TNB were tested for reversibility of the inhibition

Sites of pretranslational regulation by glucose of glucose-induced insulin release in pancreatic islets

The failure of dpp in the rescue experiment was confirmed in the nub-Gal4 domain (Fig

In summary, PROTAC technology has evolved from a conceptual degradation strategy into a clinically validated platform with tangible commercial prospects, and the impending approval of its first-in-class agents heralds its transition into an industrialization phase

GAPDH (glyceraldehyde 3-phosphate dehydrogenase) served as a loading control for total protein, while Histone-H3 was used for nuclear extracts

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