The pH-dependence of the deuterium exchange of insulin
This single reaction sits at the intersection of two critical metabolic axes: The folate cycle axis: 5-MTHF is the methyl donor that MTR uses to regenerate methionine from homocysteine, simultaneously regenerating tetrahydrofolate (THF) that feeds back into one-carbon metabolism for nucleotide synthesis (thymidylate and purine biosynthesis)
Similarly, albeit also in a small cohort, Comhair et al
Brouwers EEM, Huitema ADR, Beijnen JH, Schellens JHM (2008) Long-term platinum retention after treatment with cisplatin and oxaliplatin
La prvention suit la mme logique que pendant la grossesse : agir tt, avant que les premires stries rouges n'apparaissent
I am 53, female, and now 188