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Safety Considerations: Tirzepatide is not recommended for those with a personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, a history of pancreatitis, or severe gastrointestinal disease

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Include your doctor's letter, original medication bottles with labels, unopened syringes in sealed packages, and sharps containers

Keep the bedroom: Cool Dark Quiet Reserve the bed for sleep and intimacy only

Clinical trial results (STEP trials): Average weight loss: 15-17% of body weight At 68 weeks on 2.4mg dose: 33 pounds for a 200-pound person 86% of participants lost at least 5% body weight 50% lost at least 15% body weight This is pharmaceutical-grade weight loss

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway