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The proinflammatory cytokine IL-1 can increase TfR1 and inhibit FPN expression, promote iron transport into the cell and reduce iron efflux, and excessive iron causes mitochondrial dysfunction through the Fenton reaction
Chang SH, Stoll CRT, Song J, Varela JE, Eagon CJ, Colditz GA
Ghrelin is the primary orexigenic hormone
Hosokai Y, Nishio Y, Hirayama K, Takeda A, Ishioka T, Sawada Y, et al
Immunofluorescence staining showed that the transient amplifying cells (5-bromodeoxyuridine [BrdU + ]) were significantly increased in HG after KYP treatment indicative of stem cell activation, while no proliferating cells were observed in the control group (Fig
Furthermore, it shows significant promise in visceral obesity and metabolic syndrome research models
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