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Am J Psychiatry 175:8690

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Pathogens and the host immune response collectively dysregulate intracellular iron metabolism and ROS levels, ultimately leading to membrane damage via lipid peroxidation ( In this review, we present a comprehensive overview of ferroptosis in pathogen-related infections, discussing its implications for disease progression and treatment

Furthermore, insulin sensitivity and glucose tolerance were restored in association with increased tricarboxylic acid cycle activity in these animals on a high-fat diet through exercise intervention [77]