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With so many changes ahead, companies must stay agile, monitoring and adjusting their GLP-1 coverage strategies as the market evolves

ChemWhat Code: 1487806 Identification Physical Data Spectra Route of Synthesis (ROS) Safety and Hazards Other Data Identification Product Name Semaglutide Impurity 12 Molecular Structure CAS Registry Number N/A EINECS Number MDL Number Beilstein Registry Number Synonyms (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,48S,51S,54R,57S)-57-(((6S,12S,15S,18S,21S,24S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(2-oxo-2H-imidazol-4-yl)propanamido)-2-methylpropanamido)-48-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-51,54-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,63,72,81,86-docosaoxo-65,68,74,77-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,62,71,80,85-docosaazadohectane-1,21,84,102-tetracarboxylic acid Molecular Formula C188H290N46O61 Molecular Weight 4170.6 InChI InChI Key Canonical SMILES OC[C@H](NC([C@H](C(C)C)NC([C@@H](C(O)=O)NC([C@H](CO)NC([C@H]([C@@H](C)O)NC([C@H](CC1=CC=CC=C1)NC([C@H]([C@@H](C)O)NC(CNC([C@H](CCC(O)=O)NC(C(C)(C)NC([C@@H](N)CC2=NC(N=C2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CC3=CC=CC=C3)C(NC([C@H](CC)C)C(N[C@@H](C)C(N[C@@H](CC4=CNC5=C4C=CC=C5)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@H](C(NCC(O)=O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCCCNC(COCCOCCNC(COCCOCCNC(CCC(NC(CCCCCCCCCCCCCCCCC(O)=O)=O)C(O)=O)=O)=O)=O)=O)C)=O)C)=O)CCC(N)=O)=O)=O)=O)=O)=O)CC6=CC=C(O)C=C6)=O)=O Physical Data Appearance No data available Solubility No data available Flash Point No data available Refractive index No data available Sensitivity No data available Melting Point No data available Spectra No data available Route of Synthesis (ROS) No data available Safety and Hazards No data available Other Data HS Code 382290 Storage At room temperature and away from light Related Chemicals Use Pattern Semaglutide Impurity 12 is chemically (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,48S,51S,54R,57S)-57-(((6S,12S,15S,18S,21S,24S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(2-oxo-2H-imidazol-4-yl)propanamido)-2-methylpropanamido)-48-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-51,54-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,63,72,81,86-docosaoxo-65,68,74,77-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,62,71,80,85-docosaazadohectane-1,21,84,102-tetracarboxylic acid

Introduction into the global market has not yet been announced, so it is unclear where that supply will be produced.

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