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Nature Rev

Reassuring yourself the effects are temporary as your body adjusts

Mechanism of Action Inhibits Nicotinamide N-Methyltransferase (NNMT) Increases intracellular nicotinamide and NAD levels Improves mitochondrial efficiency and energy metabolism Supports lipolysis and fat oxidation Reduces adipocyte (fat cell) growth and proliferation Modulates inflammatory pathways and insulin signaling These effects may lead to enhanced fat metabolism, better blood sugar regulation, improved endurance, and a general increase in metabolic flexibility

Bolanos JP, Herrero-Mendez A, Fernandez-Fernandez S, Almeida A

Franziska W

Amino Acids 43 (3), 13311337