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The Phase 3 study evaluated orforglipron, an investigational, once-daily oral small molecule glucagon-like peptide-1 (GLP-1) receptor agonist, for weight maintenance over 52 weeks after initial treatment for 72 weeks with the highest tolerated doses of Wegovy (semaglutide) or Zepbound (tirzepatide), in participants from SURMOUNT-5 who were offered the opportunity to be re-randomized to receive orforglipron or placebo

The drug doesnt melt fat

Others transition to different GLP-1 agents

This product is not intended to treat, cure, diagnose, or prevent any disease

Potential Risks, Side Effects and Safety Concerns Risks include water retention, elevated IGF-1, impaired glucose tolerance, and injection site infection for CJC 1295 and ipamorelin