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Modified forms, including P7C3-A20 and P7C3-S243, have shown neuroprotection in rodent models of ALS, PD, traumatic brain injury (TBI), and age-related cognitive disorder (177)

Second, patients with chronic kidney disease (CKD) stages 3b through 5 may have impaired copper excretion through bile and urine [13]

To estimate molar concentrations a 1:1 ratio was employed

A further IPGTT study was done with a glucose challenge after 2 h of the dosing to investigate the prolonged activity of hybrids 14 , 22 and 23 (Fig