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Thus, -arrestin-1 interacts directly with GLP-1R and amplifies GLP-1 signaling and may influence -cell performance and growth

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Results The KG-dependent carnitine synthesis enzyme TMLHE is required for CCNE1-driven cell proliferation in the presence of DNA damaging agents We previously published that wildtype IDH1 and KG are increased in high grade serous ovarian cancer (HGSOC) cell lines compared to normal fallopian tube cells (Dahl et al., 2019)