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This fermentation produces gas, which expands inside the intestines and leads to digestive discomfort

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The decline in estrogen causes the body to become more insulin-resistant and lowers the resting metabolic rate

doi: 10.1016/j.biocon.2009.05.005 22 IzawaM.SakaguchiN.DoiT

Results from this trial suggested that after 28 days of treatment, the setmelanotide group demonstrated a significant mean weight reduction of 3.48 kg from baseline, accompanied by a significant decrease in mean waist circumference of 5.83 cm

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